Listed · Port St. Lucie, FL Big Shirley's BBQ & Soulfood BBQ Vitals Score8.8 / 10 What to get Reviews8.8 / 10Google 4.4★ (29 reviews) Address 10453 S U.S. Hwy 1 Port St. Lucie, FL 34952 Open in Google Maps → Add to crawl → + Add to crawl · Open planner →